Timely and accurate extraction of Adverse Drug Events (ADE) from biomedical literature is paramount for public safety, but involves slow and costly manual labor. We set out to improve drug safety monitoring (pharmacovigilance, PV) through the use of Natural Language Processing (NLP). We introduce BioDEX, a large-scale resource for Biomedical adverse Drug Event eXtraction, rooted in the historical output of drug safety reporting in the U.S. BioDEX consists of 65k abstracts and 19k full-text biomedical papers with 256k associated document-level safety reports created by medical experts. The core features of these reports include the reported weight, age, and biological sex of a patient, a set of drugs taken by the patient, the drug dosages, the reactions experienced, and whether the reaction was life threatening. In this work, we consider the task of predicting the core information of the report given its originating paper. We estimate human performance to be 72.0% F1, whereas our best model achieves 59.1% F1 (62.3 validation), indicating significant headroom. We also begin to explore ways in which these models could help professional PV reviewers. Our code and data are available at https://github.com/KarelDO/BioDEX.

We consider the task of document-level entity linking (EL), where it is important to make consistent decisions for entity mentions over the full document jointly. We aim to leverage explicit “connections” among mentions within the document itself: we propose to join EL and coreference resolution (coref) in a single structured prediction task over directed trees and use a globally normalized model to solve it. This contrasts with related works where two separate models are trained for each of the tasks and additional logic is required to merge the outputs. Experimental results on two datasets show a boost of up to +5% F1-score on both coref and EL tasks, compared to their standalone counterparts. For a subset of hard cases, with individual mentions lacking the correct EL in their candidate entity list, we obtain a +50% increase in accuracy.

We propose a newly annotated dataset for information extraction on recipes. Unlike previous approaches to machine comprehension of procedural texts, we avoid a priori pre-defining domain-specific predicates to recognize (e.g., the primitive instructionsin MILK) and focus on basic understanding of the expressed semantics rather than directly reduce them to a simplified state representation (e.g., ProPara). We thus frame the semantic comprehension of procedural text such as recipes, as fairly generic NLP subtasks, covering (i) entity recognition (ingredients, tools and actions), (ii) relation extraction (what ingredients and tools are involved in the actions), and (iii) zero anaphora resolution (link actions to implicit arguments, e.g., results from previous recipe steps). Further, our Recipe Instruction Semantic Corpus (RISeC) dataset includes textual descriptions for the zero anaphora, to facilitate language generation thereof. Besides the dataset itself, we contribute a pipeline neural architecture that addresses entity and relation extractionas well an identification of zero anaphora. These basic building blocks can facilitate more advanced downstream applications (e.g., question answering, conversational agents).

This paper describes IDLab’s text classification systems submitted to Task A as part of the CLPsych 2019 shared task. The aim of this shared task was to develop automated systems that predict the degree of suicide risk of people based on their posts on Reddit. Bag-of-words features, emotion features and post level predictions are used to derive user-level predictions. Linear models and ensembles of these models are used to predict final scores. We find that predicting fine-grained risk levels is much more difficult than flagging potentially at-risk users. Furthermore, we do not find clear added value from building richer ensembles compared to simple baselines, given the available training data and the nature of the prediction task.

This paper describes the IDLab system submitted to Task A of the CLPsych 2018 shared task. The goal of this task is predicting psychological health of children based on language used in hand-written essays and socio-demographic control variables. Our entry uses word- and character-based features as well as lexicon-based features and features derived from the essays such as the quality of the language. We apply linear models, gradient boosting as well as neural-network based regressors (feed-forward, CNNs and RNNs) to predict scores. We then make ensembles of our best performing models using a weighted average.