In this paper we argue that Frame Semantics (Fillmore, 1982) provides a good framework for semantic modelling of adjective-noun collocations. More specifically, the notion of a frame is rich enough to account for nouns from different semantic classes and to model semantic relations that hold between an adjective and a noun in terms of Frame Elements. We have substantiated these findings by considering a sample of adjective-noun collocations from German such as “enger Freund” ‘close friend’ and “starker Regen” ‘heavy rain’. The data sample is taken from different semantic fields identified in the German wordnet GermaNet (Hamp and Feldweg, 1997; Henrich and Hinrichs, 2010). The study is based on the electronic dictionary DWDS (Klein and Geyken, 2010) and uses the collocation extraction tool Wortprofil (Geyken et al., 2009). The FrameNet modelling is based on the online resource available at http://framenet.icsi.berkeley.edu. Since FrameNets are available for a range of typologically different languages, it is feasible to extend the current case study to other languages.